The Houston Texans activated big-play receiver Nico Collins from injured reserve Saturday and he will play in Sunday night’s clash against the Detroit Lions.

Collins has missed the past four games due to a hamstring injury sustained in Week 5. He was listed as questionable on Friday’s injury report.

Collins was placed on IR on Oct. 9, three days after he injured his hamstring making a 67-yard touchdown reception in the first quarter of the Texans’ 23-20 victory over the Buffalo Bills.

Collins, 25, was the NFL’s leading receiver at the time of the injury. He recorded 32 catches for 567 yards and three touchdowns in five games.

Houston also activated veteran defensive end Jerry Hughes (hip) off IR. Hughes has 70 career sacks in 222 games (152 starts) with the Indianapolis Colts (2010-12), Buffalo Bills (2013-21) and Texans.